Carbamazepine ER Tablets

Description

Generic Name: Carbamazepine
Brand Names: Tegretol XR, Carbatrol, Equetro
Important Warning
Carbamazepine may rarely cause serious or even fatal skin reactions (such as Stevens-Johnson syndrome and toxic epidermal necrolysis). The risk is higher in people of Asian descent who have a specific genetic marker (HLA-B*1502). Genetic testing may be recommended before starting treatment. Additionally, carbamazepine can cause serious blood disorders, including aplastic anemia and agranulocytosis. Regular blood tests are necessary to monitor for these conditions.

Uses for Carbamazepine ER Tablets
Carbamazepine is used to treat:

Epilepsy: To control partial seizures, generalized tonic-clonic seizures, and mixed seizure patterns.
Bipolar disorder: For managing episodes of mania or mixed episodes.
Trigeminal neuralgia: To relieve pain caused by nerve disorders affecting the face.
Before Using Carbamazepine
Allergies
Inform your doctor if you have had any allergic reactions to carbamazepine or other medications. Be sure to mention any allergies to foods, dyes, preservatives, or animals.

Pediatric and Geriatric Use
Pediatric: Safe and effective use has been established in children aged 6 years and older for seizure management.
Geriatric: Older adults may be more sensitive to the effects of carbamazepine, especially dizziness and drowsiness.
Pregnancy and Breastfeeding
Pregnancy: Carbamazepine may harm an unborn baby. Inform your doctor if you are pregnant or planning to become pregnant. Effective birth control should be used while taking this medication.
Breastfeeding: Carbamazepine passes into breast milk and may harm a nursing infant. Consult your doctor before breastfeeding.
Interactions
Medications
Carbamazepine may interact with numerous drugs. Inform your doctor if you are taking any of the following:

Blood thinners (e.g., warfarin).
Antidepressants (e.g., fluoxetine, sertraline).
Antifungals (e.g., ketoconazole).
Other seizure medications (e.g., phenytoin, valproic acid).
Hormonal contraceptives: Carbamazepine may reduce their effectiveness.
Food, Alcohol, and Tobacco
Avoid grapefruit and grapefruit juice, as they may increase the risk of side effects. Avoid alcohol, as it can increase dizziness and drowsiness.

Proper Use of Carbamazepine ER Tablets
Dosing Instructions
Take carbamazepine exactly as prescribed by your doctor. Do not crush or chew extended-release tablets; swallow them whole.
Take with food to reduce stomach upset.
Dosage
The dosage depends on the condition being treated and the patient’s response to the medication:

For Epilepsy:
Adults: Start with 200 mg twice daily. The dose may be gradually increased to 800–1200 mg/day, divided into 2 doses.
Children (6–12 years): 100 mg twice daily, adjusted as needed.
For Bipolar Disorder:
Initial dose: 200 mg twice daily. The dose may be increased gradually to a maintenance dose of 400–800 mg/day.
For Trigeminal Neuralgia:
Initial dose: 100 mg twice daily. Gradually increase by 200 mg daily until pain relief is achieved, up to a maximum of 1200 mg/day.
Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double doses.

Storage
Store at room temperature, away from heat, moisture, and light. Keep out of reach of children.

Precautions While Using Carbamazepine
Mood Monitoring: Carbamazepine may increase the risk of suicidal thoughts. Notify your doctor of any mood changes.
Avoid Driving: Carbamazepine may cause drowsiness, dizziness, or blurred vision. Do not drive or operate machinery until you know how the medication affects you.
Skin Reactions: Seek medical attention immediately if you develop a rash, blisters, or peeling skin.
Regular Blood Tests: Routine monitoring is essential to detect any blood abnormalities or liver problems.
Pregnancy Planning: Discuss family planning with your doctor. Women of childbearing age may need additional precautions while taking carbamazepine.
Side Effects of Carbamazepine ER Tablets
Serious Side Effects (Seek Immediate Medical Attention)
Unusual bleeding or bruising.
Signs of infection (e.g., fever, sore throat).
Severe skin rash or peeling.
Yellowing of the skin/eyes (jaundice).
Shortness of breath or chest pain.
Common Side Effects
Dizziness or drowsiness.
Nausea or vomiting.
Dry mouth.
Headache.
Blurred or double vision.
Rare Side Effects
Muscle weakness or tremors.
Mood changes (e.g., anxiety, depression).
Uncontrolled movements.
Emergency Situations and Overdose
Symptoms of overdose may include:

Severe dizziness or drowsiness.
Unconsciousness.
Seizures.
Irregular heartbeat.
If an overdose is suspected, seek immediate medical attention.

Contact your healthcare provider if you have any concerns or experience any side effects while taking carbamazepine.

Prescribing Information.