Isoniazid Tablets

Description

Isoniazid

Isoniazid is a medication used for the treatment of tuberculosis. It is classified as an antibiotic and works by inhibiting the synthesis of mycolic acids, a component of the bacterial cell wall. Isoniazid is typically used in combination with other medications for the treatment of tuberculosis.

Medical uses

Isoniazid is primarily used for the treatment of tuberculosis, including active tuberculosis and latent tuberculosis infection. It is used in combination with other medications, such as rifampin and pyrazinamide, for the treatment of active tuberculosis. In the treatment of latent tuberculosis infection, isoniazid may be used alone or in combination with rifapentine.

Dosage

The dosage of isoniazid will depend on the condition being treated and other factors such as age, weight, and overall health. It is typically administered orally, either as a tablet or liquid.

For the treatment of active tuberculosis, the usual adult dosage is 300mg to 900mg daily, depending on the severity of the infection. In children, the dosage is based on weight, typically ranging from 10mg to 20mg per kg of body weight.

For the treatment of latent tuberculosis infection, the usual adult dosage is 300mg daily for six to nine months. In children, the dosage is based on weight, typically ranging from 10mg to 20mg per kg of body weight.

Side effects

Common side effects of isoniazid include nausea, vomiting, and loss of appetite. Other possible side effects include peripheral neuropathy, hepatotoxicity, and blood disorders.

Precautions

Isoniazid may interact with other medications, including antacids, phenytoin, and certain antibiotics. It should not be used in individuals with liver disease, active tuberculosis of the liver, or a history of severe adverse reactions to isoniazid.

Isoniazid should be used with caution in individuals with a history of alcohol abuse or liver disease. Regular liver function tests are recommended during treatment with isoniazid.

Pregnancy and breastfeeding

Isoniazid is generally considered safe to use during pregnancy and breastfeeding. However, it is important to discuss the potential risks and benefits with a healthcare provider before using this medication.

Overdose

Symptoms of an overdose of isoniazid may include seizures, confusion, and coma. If an overdose is suspected, immediate medical attention should be sought.

Storage

Isoniazid should be stored at room temperature, away from moisture and heat.

Conclusion

Isoniazid is a medication used for the treatment of tuberculosis. It works by inhibiting the synthesis of mycolic acids, a component of the bacterial cell wall. Isoniazid is typically used in combination with other medications for the treatment of tuberculosis. Common side effects include nausea, vomiting, and loss of appetite. It should be used with caution in individuals with a history of alcohol abuse or liver disease. Regular liver function tests are recommended during treatment with isoniazid.