Midodrine Tablets

Description

Generic Name: Midodrine
Brand Name: ProAmatine
Important Warning
Midodrine is used to treat orthostatic hypotension (a condition where blood pressure drops when standing, causing dizziness or fainting). This medication should only be used in patients whose daily lives are severely affected by this condition and for whom other treatments have not worked. Midodrine can increase blood pressure when lying down (supine hypertension). Patients should be monitored regularly, and the medication should be discontinued if supine hypertension cannot be managed.

Uses for Midodrine Tablets
Midodrine is prescribed for the treatment of:

Orthostatic Hypotension: It helps improve blood pressure and reduces symptoms like dizziness and lightheadedness caused by low blood pressure when standing.
Midodrine works by constricting blood vessels, which increases blood pressure.

Before Using Midodrine
Allergies
Inform your doctor if you have any allergies to midodrine or any other medications. Mention any allergic reactions to foods, dyes, preservatives, or animals.

Pediatric and Geriatric Use
Pediatric: Safety and effectiveness have not been established in children.
Geriatric: Older adults may be more sensitive to the effects of midodrine, especially supine hypertension.
Pregnancy and Breastfeeding
Pregnancy: There is limited information on the safety of midodrine during pregnancy. Use only if clearly needed and directed by your doctor.
Breastfeeding: It is unknown if midodrine passes into breast milk. Consult your healthcare provider before breastfeeding.
Interactions
Medications
Inform your doctor if you are taking any of the following, as they may interact with midodrine:

Alpha blockers: (e.g., doxazosin, prazosin)
Beta blockers: (e.g., metoprolol, propranolol)
Heart medications: (e.g., digoxin)
MAO inhibitors: (e.g., phenelzine, tranylcypromine)
Diuretics or other blood pressure medications
Food, Alcohol, and Tobacco
Avoid alcohol while taking midodrine, as it may worsen dizziness or lower blood pressure further.

Proper Use of Midodrine Tablets
Dosing Instructions
Take midodrine exactly as prescribed by your doctor.
Typically taken 3 times daily (morning, midday, and late afternoon).
Avoid taking it within 4 hours of bedtime to reduce the risk of high blood pressure while lying down (supine hypertension).
Dosage
The dosage depends on the condition being treated and individual response:

Adults: 10 mg three times daily.
Children: Not recommended unless directed by a doctor.
Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose. Do not double doses.

Storage
Store midodrine tablets at room temperature, away from moisture, heat, and light. Keep out of reach of children.

Precautions While Using Midodrine
Supine Hypertension: Avoid lying flat for long periods. Elevate the head of your bed to prevent high blood pressure while lying down.
Regular Monitoring: Regular blood pressure checks are necessary to ensure safe use of midodrine.
Avoid Heavy Physical Activity: Strenuous activity may cause rapid changes in blood pressure.
Side Effects of Midodrine Tablets
Serious Side Effects (Seek Immediate Medical Attention)
Severe headache or blurred vision (possible sign of high blood pressure).
Slow or irregular heartbeat.
Difficulty urinating.
Tingling or coldness in the hands and feet.
Severe dizziness or fainting.
Common Side Effects
Itching or tingling of the scalp.
Chills or goosebumps.
Frequent urination.
Nausea.
Rare Side Effects
Anxiety or nervousness.
Skin rash.
Emergency Situations and Overdose
Symptoms of overdose may include:

Severe high blood pressure.
Severe dizziness or fainting.
Slow or irregular heartbeat.
If an overdose is suspected, seek immediate medical attention.

Contact your healthcare provider if you experience any concerning symptoms or side effects while taking midodrine.

Labeling Information.

MedlinePlus Drug Information.